The ChemoGuide project will clinically validate a proto-type technology (2treat) developed in the previous "Research for SMEs" project, "Integrated Chemical Synthesis and Cell screening in patient cells (ICSC)". The project will execute a clinical study to evaluate the test's capability of predicting which combination therapy that is most efficacious and show no resistance in the individual colorectal cancer patient. The prediction is based on reading the cell functional output cancer cells isolated from the individual patient. The clinical study will serve to verify the capability and robustness of the test.